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Integrated Method for Purification and Single-Particle Characterization of Lentiviral Vector Systems by Size Exclusion Chromatography and Tunable Resistive Pulse Sensing

Elements derived from lentiviral particles such as viral vectors or virus-like particles are commonly used for biotechnological and biomedical applications, for example in mammalian protein expression, gene delivery or therapy, and vaccine development. Preparations of high purity are necessary in mo...

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Библиографические подробности
Опубликовано в: :Mol Biotechnol
Главные авторы: Heider, Susanne, Muzard, Julien, Zaruba, Marianne, Metzner, Christoph
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486506/
https://ncbi.nlm.nih.gov/pubmed/28567687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-017-0009-8
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