Rapid In-Process Monitoring of Lentiviral Vector Particles by High-Performance Liquid Chromatography

Lentiviral vectors (LVs) are a popular gene delivery tool in cell and gene therapy and they are a primary tool for ex vivo transduction of T cells for expression of chimeric antigen receptor (CAR) in CAR-T cell therapies. Extensive process and product characterization are required in manufacturing v...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther Methods Clin Dev
Hoofdauteurs: Transfiguracion, Julia, Tran, Michelle Yen, Lanthier, Stéphane, Tremblay, Sonia, Coulombe, Nathalie, Acchione, Mauro, Kamen, Amine A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2020
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479275/
https://ncbi.nlm.nih.gov/pubmed/32953931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.08.005
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