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Can computed crystal energy landscapes help understand pharmaceutical solids?

Computational crystal structure prediction (CSP) methods can now be applied to the smaller pharmaceutical molecules currently in drug development. We review the recent uses of computed crystal energy landscapes for pharmaceuticals, concentrating on examples where they have been used in collaboration...

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Publicado en:Chem Commun (Camb)
Main Authors: Price, Sarah L., Braun, Doris E., Reutzel-Edens, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486446/
https://ncbi.nlm.nih.gov/pubmed/27067116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc00721j
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