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Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity.

The ras gene product (p21) is a GTP-binding protein and has been thought to transduce signals regulating proliferation or differentiation of cells. Like other GTP-binding proteins, p21.GTP is an active conformation, which can transduce the signals downstream, whereas p21.GDP is an inactive one. Rece...

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Bibliografische gegevens
Hoofdauteurs: Satoh, T, Endo, M, Nakafuku, M, Akiyama, T, Yamamoto, T, Kaziro, Y
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1990
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC54864/
https://ncbi.nlm.nih.gov/pubmed/2146678
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