The Thr300Ala variant of ATG16L1 is associated with decreased risk of brain metastasis in patients with non-small cell lung cancer

Non-small cell lung cancer (NSCLC) often metastasizes to the brain, but identifying which patients will develop brain metastases (BM) is difficult. Macroautophagy/autophagy is critical for cancer initiation and progression. We hypothesized that genetic variants of autophagy-related genes may affect...

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Podrobná bibliografie
Vydáno v:Autophagy
Hlavní autoři: Li, Qian-xia, Zhou, Xiao, Huang, Ting-ting, Tang, Yang, Liu, Bo, Peng, Ping, Sun, Li, Wang, Yi-hua, Yuan, Xiang-lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Clinical Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486363/
https://ncbi.nlm.nih.gov/pubmed/28441070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1308997
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