Efficacy of vaccination with tumor-exosome loaded dendritic cells combined with cytotoxic drug treatment in pancreatic cancer

Pancreatic cancer (PaCa) has a dismal prognosis and adjuvant immunotherapy frequently is of low efficacy due to immunosuppressive features of PaCa and PaCa-stroma. We here explored, whether the efficacy of vaccination with tumor-exosome (TEX)-loaded dendritic cells (DC) can be improved by combining...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Xiao, Li, Erb, Ulrike, Zhao, Kun, Hackert, Thilo, Zöller, Margot
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486185/
https://ncbi.nlm.nih.gov/pubmed/28680753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1319044
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