CD44v6-competent tumor exosomes promote motility, invasion and cancer-initiating cell marker expression in pancreatic and colorectal cancer cells

Cancer-initiating cells (CIC) account for metastatic spread, which may rely mostly on CIC exosomes (TEX) that affect host cells and can transfer CIC features into Non-CIC. The CIC marker CD44 variant isoform v6 (CD44v6) being known for metastasis-promotion, we elaborated in cells its contribution to...

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發表在:Oncotarget
Main Authors: Wang, Zhe, von Au, Anja, Schnölzer, Martina, Hackert, Thilo, Zöller, Margot
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342426/
https://ncbi.nlm.nih.gov/pubmed/27419629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10580
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