Chemotherapeutic tumor microparticles combining low-dose irradiation reprogram tumor-promoting macrophages through a tumor-repopulating cell-curtailing pathway

Stem cell-like tumor-repopulating cells (TRCs) have a critical role in establishing a tumor immunosuppressive microenvironment. However, means to enhance antitumor immunity by disrupting TRCs are absent. Our previous studies have shown that tumor cell-derived microparticles (T-MPs) preferentially ab...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Sun, Yanling, Zheng, Zu'an, Zhang, Huafeng, Yu, Yuandong, Ma, Jingwei, Tang, Ke, Xu, Pingwei, Ji, Tiantian, Liang, Xiaoyu, Chen, Degao, Jin, Xun, Zhang, Tianzhen, Long, Zhixiong, Liu, Yuying, Huang, Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486181/
https://ncbi.nlm.nih.gov/pubmed/28680743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1309487
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