Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment

We have previously reported that direct injection of dendritic cells (DC) engineered to express the Type-1 transactivator Tbet (i.e., DC.Tbet) into murine tumors results in antitumor efficacy in association with the development of structures resembling tertiary lymphoid organs (TLO) in the tumor mic...

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Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Weinstein, Aliyah M., Chen, Lu, Brzana, Emily A., Patil, Prashanti R., Taylor, Jennifer L., Fabian, Kellsye L., Wallace, Callen T., Jones, Sabrina D., Watkins, Simon C., Lu, Binfeng, Stroncek, David F., Denning, Timothy L., Fu, Yang-Xin, Cohen, Peter A., Storkus, Walter J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2017
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486180/
https://ncbi.nlm.nih.gov/pubmed/28680760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1322238
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