Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment

We have previously reported that direct injection of dendritic cells (DC) engineered to express the Type-1 transactivator Tbet (i.e., DC.Tbet) into murine tumors results in antitumor efficacy in association with the development of structures resembling tertiary lymphoid organs (TLO) in the tumor mic...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Weinstein, Aliyah M., Chen, Lu, Brzana, Emily A., Patil, Prashanti R., Taylor, Jennifer L., Fabian, Kellsye L., Wallace, Callen T., Jones, Sabrina D., Watkins, Simon C., Lu, Binfeng, Stroncek, David F., Denning, Timothy L., Fu, Yang-Xin, Cohen, Peter A., Storkus, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486180/
https://ncbi.nlm.nih.gov/pubmed/28680760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1322238
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