IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils

The alarmin IL-33 is an IL-1 family member that stimulates pleiotropic immune reactions depending on the target tissue and microenvironmental factors. In this study, we have investigated the role of IL-33/ST2 axis in antitumor response to melanoma. Injection of IL-33 in mice-bearing subcutaneous B16...

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Veröffentlicht in:Oncoimmunology
Hauptverfasser: Lucarini, Valeria, Ziccheddu, Giovanna, Macchia, Iole, La Sorsa, Valentina, Peschiaroli, Francesca, Buccione, Carla, Sistigu, Antonella, Sanchez, Massimo, Andreone, Sara, D'Urso, Maria Teresa, Spada, Massimo, Macchia, Daniele, Afferni, Claudia, Mattei, Fabrizio, Schiavoni, Giovanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486175/
https://ncbi.nlm.nih.gov/pubmed/28680750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1317420
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