The Pleiotropic Immunomodulatory Functions of IL-33 and Its Implications in Tumor Immunity

Interleukin-33 (IL-33) is a IL-1 family member of cytokines exerting pleiotropic activities. In the steady-state, IL-33 is expressed in the nucleus of epithelial, endothelial, and fibroblast-like cells acting as a nuclear protein. In response to tissue damage, infections or necrosis IL-33 is release...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Afferni, Claudia, Buccione, Carla, Andreone, Sara, Galdiero, Maria Rosaria, Varricchi, Gilda, Marone, Gianni, Mattei, Fabrizio, Schiavoni, Giovanna
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242976/
https://ncbi.nlm.nih.gov/pubmed/30483263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02601
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