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PD-1/PD-L1 Blockade Therapy for Tumors with Downregulated MHC Class I Expression

The therapy of different advanced-stage malignancies with monoclonal antibodies blocking programmed cell death protein 1 (PD-1)/PD-1 ligand 1 (PD-L1) signaling has had an impressive long-lasting effect in a portion of patients, but in most cases, this therapy was not successful, or a secondary resis...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteur principal: Šmahel, Michal
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486151/
https://ncbi.nlm.nih.gov/pubmed/28635644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061331
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