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Hypoxic Preconditioning Promotes the Bioactivities of Mesenchymal Stem Cells via the HIF-1α-GRP78-Akt Axis

Mesenchymal stem cells (MSC) are ideal materials for stem cell-based therapy. As MSCs reside in hypoxic microenvironments (low oxygen tension of 1% to 7%), several studies have focused on the beneficial effects of hypoxic preconditioning on MSC survival; however, the mechanisms underlying such effec...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lee, Jun Hee, Yoon, Yeo Min, Lee, Sang Hun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486141/
https://ncbi.nlm.nih.gov/pubmed/28635661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061320
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