Optimization of Polyplex Formation between DNA Oligonucleotide and Poly(l-Lysine): Experimental Study and Modeling Approach

The polyplexes formed by nucleic acids and polycations have received a great attention owing to their potential application in gene therapy. In our study, we report experimental results and modeling outcomes regarding the optimization of polyplex formation between the double-stranded DNA (dsDNA) and...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Vasiliu, Tudor, Cojocaru, Corneliu, Rotaru, Alexandru, Pricope, Gabriela, Pinteala, Mariana, Clima, Lilia
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486112/
https://ncbi.nlm.nih.gov/pubmed/28629130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061291
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