Independent versus Cooperative Binding in Polyethylenimine–DNA and Poly(L-lysine)–DNA Polyplexes

The mechanism of polyethylenimine–DNA and poly(L-lysine)–DNA complex formation at pH 5.2 and 7.4 was studied by a time-resolved spectroscopic method. The formation of a polyplex core was observed to be complete at approximately N/P = 2, at which point nearly all DNA phosphate groups were bound by po...

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Bibliografiske detaljer
Main Authors: Ketola, Tiia-Maaria, Hanzlíková, Martina, Leppänen, Linda, Raviña, Manuela, Bishop, Corey J., Green, Jordan J., Urtti, Arto, Lemmetyinen, Helge, Yliperttula, Marjo, Vuorimaa-Laukkanen, Elina
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888923/
https://ncbi.nlm.nih.gov/pubmed/23941196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp404812a
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