Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols

Human induced pluripotent stem cells (iPSCs) represent a powerful human model to study cardiac disease in vitro, notably channelopathies and sarcomeric cardiomyopathies. Different protocols for cardiac differentiation of iPSCs have been proposed either based on embroid body formation (3D) or, more r...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jeziorowska, Dorota, Fontaine, Vincent, Jouve, Charlène, Villard, Eric, Dussaud, Sébastien, Akbar, David, Letang, Valérie, Cervello, Pauline, Itier, Jean-Michiel, Pruniaux, Marie-Pierre, Hulot, Jean-Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485997/
https://ncbi.nlm.nih.gov/pubmed/28587156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061173
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