Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols

Human induced pluripotent stem cells (iPSCs) represent a powerful human model to study cardiac disease in vitro, notably channelopathies and sarcomeric cardiomyopathies. Different protocols for cardiac differentiation of iPSCs have been proposed either based on embroid body formation (3D) or, more r...

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Udgivet i:Int J Mol Sci
Main Authors: Jeziorowska, Dorota, Fontaine, Vincent, Jouve, Charlène, Villard, Eric, Dussaud, Sébastien, Akbar, David, Letang, Valérie, Cervello, Pauline, Itier, Jean-Michiel, Pruniaux, Marie-Pierre, Hulot, Jean-Sébastien
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485997/
https://ncbi.nlm.nih.gov/pubmed/28587156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061173
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