Mismatch repair deficiency screening in colorectal carcinoma by a four-antibody immunohistochemical panel in Pakistani population and its correlation with histopathological parameters

BACKGROUND: Microsatellite instability (MSI) operates as the second major pathway in the colorectal carcinogenesis. Although genetic testing remains the gold standard for the detection of MSI, the College of American Pathologists (CAP) recommends an initial immunohistochemical workup with a four-ant...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:World J Surg Oncol
Autori principali: Hashmi, Atif Ali, Ali, Rabia, Hussain, Zubaida Fida, Faridi, Naveen, Khan, Erum Yousuf, Bakar, Syed Muhammad Abu, Edhi, Muhammad Muzzammil, Khan, Mehmood
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485685/
https://ncbi.nlm.nih.gov/pubmed/28651545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-017-1158-8
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