Mismatch repair deficiency screening in colorectal carcinoma by a four-antibody immunohistochemical panel in Pakistani population and its correlation with histopathological parameters

BACKGROUND: Microsatellite instability (MSI) operates as the second major pathway in the colorectal carcinogenesis. Although genetic testing remains the gold standard for the detection of MSI, the College of American Pathologists (CAP) recommends an initial immunohistochemical workup with a four-ant...

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Bibliographic Details
Published in:World J Surg Oncol
Main Authors: Hashmi, Atif Ali, Ali, Rabia, Hussain, Zubaida Fida, Faridi, Naveen, Khan, Erum Yousuf, Bakar, Syed Muhammad Abu, Edhi, Muhammad Muzzammil, Khan, Mehmood
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485685/
https://ncbi.nlm.nih.gov/pubmed/28651545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-017-1158-8
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