Suppression Of β-catenin Nuclear Translocation By CGP57380 Decelerates Poor Progression And Potentiates Radiation-Induced Apoptosis in Nasopharyngeal Carcinoma

Nuclear localization of β-catenin is essential for the progression of various human cancers via transcriptional upregulation of downstream genes. The MAP kinase interacting serine/threonine kinase (MNK)-eukaryotic translation initiation factor 4E (eIF4E) axis has been reported to activate Wnt/β-cate...

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Vydáno v:Theranostics
Hlavní autoři: Wang, Weiyuan, Wen, Qiuyuan, Luo, Jiadi, Chu, Shuzhou, Chen, Lingjiao, Xu, Lina, Zang, Hongjing, Alnemah, Mohannad Ma, Li, Jinghe, Zhou, Jianhua, Fan, Songqing
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485425/
https://ncbi.nlm.nih.gov/pubmed/28656063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.17665
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