A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia–reperfusion injury

The cytokine erythropoietin (EPO) protects the heart from ischemic injury, in part by preventing apoptosis. However, EPO administration can also raise the hemoglobin concentration, which, by increasing oxygen delivery, confounds assignment of cause and effect. The availability of EPO analogs that do...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Fiordaliso, Fabio, Chimenti, Stefano, Staszewsky, Lidia, Bai, Antonio, Carlo, Eleonora, Cuccovillo, Ivan, Doni, Mirko, Mengozzi, Manuela, Tonelli, Rossella, Ghezzi, Pietro, Coleman, Thomas, Brines, Michael, Cerami, Anthony, Latini, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548534/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15671158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409329102
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