A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia–reperfusion injury

The cytokine erythropoietin (EPO) protects the heart from ischemic injury, in part by preventing apoptosis. However, EPO administration can also raise the hemoglobin concentration, which, by increasing oxygen delivery, confounds assignment of cause and effect. The availability of EPO analogs that do...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Fiordaliso, Fabio, Chimenti, Stefano, Staszewsky, Lidia, Bai, Antonio, Carlo, Eleonora, Cuccovillo, Ivan, Doni, Mirko, Mengozzi, Manuela, Tonelli, Rossella, Ghezzi, Pietro, Coleman, Thomas, Brines, Michael, Cerami, Anthony, Latini, Roberto
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548534/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15671158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409329102
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