Comparative transcriptome analysis of isogenic cell line models and primary cancers links capicua (CIC) loss to activation of the MAPK signalling cascade

CIC encodes a transcriptional repressor, capicua (CIC), whose disrupted activity appears to be involved in several cancer types, including type I low‐grade gliomas (LGGs) and stomach adenocarcinomas (STADs). To explore human CIC's transcriptional network in an isogenic background, we developed...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Pathol
Auteurs principaux: LeBlanc, Veronique G, Firme, Marlo, Song, Jungeun, Chan, Susanna Y, Lee, Min Hye, Yip, Stephen, Chittaranjan, Suganthi, Marra, Marco A
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd 2017
Sujets:
Original Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485162/
https://ncbi.nlm.nih.gov/pubmed/28295365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4894
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