Multivalent Peptide–Nanoparticle Conjugates for Influenza‐Virus Inhibition

To inhibit binding of the influenza A virus to the host cell glycocalyx, we generate multivalent peptide–polymer nanoparticles binding with nanomolar affinity to the virus via its spike protein hemagglutinin. The chosen dendritic polyglycerol scaffolds are highly biocompatible and well suited for a...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Lauster, Daniel, Glanz, Maria, Bardua, Markus, Ludwig, Kai, Hellmund, Markus, Hoffmann, Ute, Hamann, Alf, Böttcher, Christoph, Haag, Rainer, Hackenberger, Christian P. R., Herrmann, Andreas
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485077/
https://ncbi.nlm.nih.gov/pubmed/28444849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201702005
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