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Multivalent Peptide–Nanoparticle Conjugates for Influenza‐Virus Inhibition

To inhibit binding of the influenza A virus to the host cell glycocalyx, we generate multivalent peptide–polymer nanoparticles binding with nanomolar affinity to the virus via its spike protein hemagglutinin. The chosen dendritic polyglycerol scaffolds are highly biocompatible and well suited for a...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Lauster, Daniel, Glanz, Maria, Bardua, Markus, Ludwig, Kai, Hellmund, Markus, Hoffmann, Ute, Hamann, Alf, Böttcher, Christoph, Haag, Rainer, Hackenberger, Christian P. R., Herrmann, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485077/
https://ncbi.nlm.nih.gov/pubmed/28444849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201702005
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