Estradiol Regulates Susceptibility following Primary Exposure to Genital Herpes Simplex Virus Type 2, while Progesterone Induces Inflammation

We report here that sex hormones modulate susceptibility to a sexually transmitted viral agent, herpes simplex virus type 2 (HSV-2), in a mouse model. Ovariectomized mice were administered either saline (control), estradiol (E(2)), progesterone (P(4)), or a combination of both estradiol and progeste...

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Hauptverfasser: Gillgrass, Amy E., Fernandez, Sherie A., Rosenthal, Kenneth L., Kaushic, Charu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC548484/
https://ncbi.nlm.nih.gov/pubmed/15709030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.3107-3116.2005
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