Prolonged Exposure to Progesterone Prevents Induction of Protective Mucosal Responses following Intravaginal Immunization with Attenuated Herpes Simplex Virus Type 2

Depo-Provera (Depo) is a long-acting progestational formulation that is a popular form of contraception for women. In animal models of sexually transmitted diseases, it is used to facilitate infection. Here we report that treatment with Depo, in a mouse model of genital herpes simplex virus type 2 (...

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Bibliographic Details
Main Authors: Gillgrass, Amy E., Ashkar, Ali A., Rosenthal, Kenneth L., Kaushic, Charu
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC224606/
https://ncbi.nlm.nih.gov/pubmed/12941893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.9845-9851.2003
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