The potential role of sensory testing, skin biopsy, and functional brain imaging as biomarkers in chronic pain clinical trials: IMMPACT considerations

Valid and reliable biomarkers can play an important role in clinical trials as indicators of biological or pathogenic processes or as a signal of treatment response. Currently, there are no biomarkers for pain qualified by the US Food and Drug Administration or the European Medicines Agency for use...

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Detalhes bibliográficos
Publicado no:J Pain
Main Authors: Smith, Shannon M., Dworkin, Robert H., Turk, Dennis C., Baron, Ralf, Polydefkis, Michael, Tracey, Irene, Borsook, David, Edwards, Robert R., Harris, Richard E., Wager, Tor D., Arendt-Nielsen, Lars, Burke, Laurie B., Carr, Daniel B., Chappell, Amy, Farrar, John T., Freeman, Roy, Gilron, Ian, Goli, Veeraindar, Haeussler, Juergen, Jensen, Troels, Katz, Nathaniel P., Kent, Jeffrey, Kopecky, Ernest A., Lee, David A., Maixner, William, Markman, John D., McArthur, Justin C., McDermott, Michael P., Parvathenani, Lav, Raja, Srinivasa N., Rappaport, Bob A., Rice, Andrew S. C., Rowbotham, Michael C., Tobias, Jeffrey K., Wasan, Ajay D., Witter, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484729/
https://ncbi.nlm.nih.gov/pubmed/28254585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2017.02.429
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