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Research design considerations for clinical studies of abuse-deterrent opioid analgesics: IMMPACT recommendations

Opioids are essential to the management of pain in many patients, but they also are associated with potential risks for abuse, overdose, and diversion. A number of efforts have been devoted to the development of abuse-deterrent formulations of opioids to reduce these risks. This article summarizes a...

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Autori principali: Turk, Dennis C., O’Connor, Alec B., Dworkin, Robert H., Chaudhry, Amina, Katz, Nathaniel P., Adams, Edgar H., Brownstein, John S., Comer, Sandra D., Dart, Richard, Dasgupta, Nabarun, Denisco, Richard A., Klein, Michael, Leiderman, Deborah B., Lubran, Robert, Rappaport, Bob A., Zacny, James P., Ahdieh, Harry, Burke, Laurie B., Cowan, Penney, Jacobs, Petra, Malamut, Richard, Markman, John, Michna, Edward, Palmer, Pamela, Peirce-Sandner, Sarah, Potter, Jennifer S., Raja, Srinivasa N., Rauschkolb, Christine, Roland, Carl L., Webster, Lynn R., Weiss, Roger D., Wolf, Kerry
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617214/
https://ncbi.nlm.nih.gov/pubmed/22770841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2012.05.029
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