Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival

Myelin, made by oligodendrocytes, is essential for rapid information transfer in the central nervous system. Oligodendrocyte precursors (OPs) receive glutamatergic synaptic input from axons but how this affects their development is unclear. Murine OPs in white matter express AMPA receptor (AMPAR) su...

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Gepubliceerd in:eLife
Hoofdauteurs: Kougioumtzidou, Eleni, Shimizu, Takahiro, Hamilton, Nicola B, Tohyama, Koujiro, Sprengel, Rolf, Monyer, Hannah, Attwell, David, Richardson, William D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2017
Onderwerpen:
Developmental Biology and Stem Cells
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484614/
https://ncbi.nlm.nih.gov/pubmed/28608780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28080
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