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Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival

Myelin, made by oligodendrocytes, is essential for rapid information transfer in the central nervous system. Oligodendrocyte precursors (OPs) receive glutamatergic synaptic input from axons but how this affects their development is unclear. Murine OPs in white matter express AMPA receptor (AMPAR) su...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kougioumtzidou, Eleni, Shimizu, Takahiro, Hamilton, Nicola B, Tohyama, Koujiro, Sprengel, Rolf, Monyer, Hannah, Attwell, David, Richardson, William D
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484614/
https://ncbi.nlm.nih.gov/pubmed/28608780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28080
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