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Insufficient Astrocyte-Derived BDNF Contributes to Propofol-Induced Neuron Death through Akt/GSK3β/Mitochondrial Fission Pathway
BACKGROUND: Growing animal evidence demonstrates that prolonged exposure to propofol during brain development induces widespread neuronal cell death, but there is little information on the role of astrocytes. Astrocytes can release neurotropic growth factors such as brain-derived neurotropic factor...
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| Publicado no: | Anesth Analg |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484590/ https://ncbi.nlm.nih.gov/pubmed/28622174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000002137 |
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