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Propofol Alters Long Non-Coding RNA Profiles in the Neonatal Mouse Hippocampus: Implication of Novel Mechanisms in Anesthetic-Induced Developmental Neurotoxicity

BACKGROUND: Propofol induces acute neurotoxicity (e.g., neuroapoptosis) followed by impairment of long-term memory and learning in animals. However, underlying mechanisms remain largely unknown. Long non-coding RNAs (lncRNAs) are found to participate in various pathological processes. We hypothesize...

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Detalhes bibliográficos
Publicado no:Cell Physiol Biochem
Main Authors: Logan, Sarah, Jiang, Congshan, Yan, Yasheng, Inagaki, Yasuyoshi, Arzua, Thiago, Bai, Xiaowen
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221186/
https://ncbi.nlm.nih.gov/pubmed/30261491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000493875
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