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Role of adipose tissue endothelial ADAM17 in age-related coronary microvascular dysfunction
OBJECTIVE: A disintegrin and metalloproteinase ADAM17 (TNF-α converting enzyme) regulates soluble TNF levels. We tested the hypothesis that aging-induced activation in adipose tissue (AT)-expressed ADAM17 contributes to the development of remote coronary microvascular dysfunction (CMD) in obesity. A...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484536/ https://ncbi.nlm.nih.gov/pubmed/28473444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309430 |
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