Interferon signaling in Peromyscus leucopus confers a potent and specific restriction to vector-borne flaviviruses

Tick-borne flaviviruses (TBFVs), including Powassan virus and tick-borne encephalitis virus cause encephalitis or hemorrhagic fevers in humans with case-fatality rates ranging from 1–30%. Despite severe disease in humans, TBFV infection of natural rodent hosts has little noticeable effect. Currently...

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Udgivet i:PLoS One
Main Authors: Izuogu, Adaeze O., McNally, Kristin L., Harris, Stephen E., Youseff, Brian H., Presloid, John B., Burlak, Christopher, Munshi-South, Jason, Best, Sonja M., Taylor, R. Travis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484488/
https://ncbi.nlm.nih.gov/pubmed/28650973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179781
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