TRAF6 Plays a Proviral Role in Tick-Borne Flavivirus Infection through Interaction with the NS3 Protease

Tick-borne flaviviruses (TBFVs) can cause life-threatening encephalitis and hemorrhagic fever. To identify virus-host interactions that may be exploited as therapeutic targets, we analyzed the TBFV polyprotein in silico for antiviral protein-binding motifs. We obtained two putative tumor necrosis fa...

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Bibliographic Details
Published in:iScience
Main Authors: Youseff, Brian H., Brewer, Thomas G., McNally, Kristin L., Izuogu, Adaeze O., Lubick, Kirk J., Presloid, John B., Alqahtani, Saad, Chattopadhyay, Saurabh, Best, Sonja M., Hu, Xiche, Taylor, R. Travis
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536497/
https://ncbi.nlm.nih.gov/pubmed/31129244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.05.010
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