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Limitations of the hCMEC/D3 cell line as a model for Aβ clearance by the human blood‐brain barrier

Alzheimer's disease and cerebral amyloid angiopathy are characterized by accumulation of amyloid‐β (Aβ) at the cerebrovasculature due to decreased clearance at the blood‐brain barrier (BBB). However, the exact mechanism of Aβ clearance across this barrier has not been fully elucidated. The hCME...

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Detalles Bibliográficos
Publicado en:J Neurosci Res
Main Authors: Biemans, Elisanne A.L.M., Jäkel, Lieke, de Waal, Robert M.W., Kuiperij, H. Bea, Verbeek, Marcel M.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484315/
https://ncbi.nlm.nih.gov/pubmed/27726164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23964
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