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Reduced Influence of apoE on Aβ43 Aggregation and Reduced Vascular Aβ43 Toxicity as Compared with Aβ40 and Aβ42

The amyloid-β 43 (Aβ43) peptide has been shown to be abundantly expressed in Alzheimer’s disease plaques, whereas only relatively low levels have been demonstrated in cerebral amyloid angiopathy (CAA). To better understand this discrepant distribution, we studied various biochemical properties of Aβ...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Jäkel, Lieke, Biemans, Elisanne A.L.M., Klijn, Catharina J.M., Kuiperij, H. Bea, Verbeek, Marcel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118029/
https://ncbi.nlm.nih.gov/pubmed/31953617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-01873-x
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