Nonstructural Protein σ1s Is a Determinant of Reovirus Virulence and Influences the Kinetics and Severity of Apoptosis Induction in the Heart and Central Nervous System

The mechanisms by which viruses kill susceptible cells in target organs and ultimately produce disease in the infected host remain poorly understood. Dependent upon the site of inoculation and strain of virus, experimental infection of neonatal mice with reoviruses can induce fatal encephalitis or m...

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Bibliografiske detaljer
Main Authors: Hoyt, Cristen C., Richardson-Burns, Sarah M., Goody, Robin J., Robinson, Bridget A., DeBiasi, Roberta L., Tyler, Kenneth L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC548430/
https://ncbi.nlm.nih.gov/pubmed/15708993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.2743-2753.2005
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