Nonstructural Protein σ1s Is a Determinant of Reovirus Virulence and Influences the Kinetics and Severity of Apoptosis Induction in the Heart and Central Nervous System

The mechanisms by which viruses kill susceptible cells in target organs and ultimately produce disease in the infected host remain poorly understood. Dependent upon the site of inoculation and strain of virus, experimental infection of neonatal mice with reoviruses can induce fatal encephalitis or m...

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Detalhes bibliográficos
Main Authors: Hoyt, Cristen C., Richardson-Burns, Sarah M., Goody, Robin J., Robinson, Bridget A., DeBiasi, Roberta L., Tyler, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548430/
https://ncbi.nlm.nih.gov/pubmed/15708993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.2743-2753.2005
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