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Fluoroacetamide Moieties as NMR Spectroscopy Probes for the Molecular Recognition of GlcNAc‐Containing Sugars: Modulation of the CH–π Stacking Interactions by Different Fluorination Patterns

We herein propose the use of fluoroacetamide and difluoroacetamide moieties as sensitive tags for the detection of sugar–protein interactions by simple (1)H and/or (19)F NMR spectroscopy methods. In this process, we have chosen the binding of N,N′‐diacetyl chitobiose, a ubiquitous disaccharide fragm...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Unione, Luca, Alcalá, Maria, Echeverria, Begoña, Serna, Sonia, Ardá, Ana, Franconetti, Antonio, Cañada, F. Javier, Diercks, Tammo, Reichardt, Niels, Jiménez‐Barbero, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484281/
https://ncbi.nlm.nih.gov/pubmed/28124793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201605573
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