Roles of Tumor Necrosis Factor Alpha (TNF-α) and the p55 TNF Receptor in CD1d Induction and Coxsackievirus B3-Induced Myocarditis

Giving C57BL/6 mice 10(4) PFU of coxsackievirus B3 (H3 variant) fails to induce myocarditis, but increasing the initial virus inoculum to 10(5) or 10(6) PFU causes significant cardiac disease. Virus titers in the heart were equivalent at days 3 and 7 in mice given all three virus doses, but day 3 ti...

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Bibliographic Details
Main Authors: Huber, S. A., Sartini, D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC548425/
https://ncbi.nlm.nih.gov/pubmed/15708985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.2659-2665.2005
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