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A Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA

Nicotinic acetylcholine receptors (nAChRs) play a fundamental role in nervous signal transmission, therefore various antagonists and agonists are highly desired to explore the structure and function of nAChRs. Recently, a novel dimeric αD-conotoxin GeXXA was identified to inhibit nAChRs by binding a...

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Опубликовано в: :Mar Drugs
Главные авторы: Yang, Longjin, Tae, Han-Shen, Fan, Zhou, Shao, Xiaoxia, Xu, Shaoqiong, Zhao, Suwen, Adams, David J., Wang, Chunguang
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484114/
https://ncbi.nlm.nih.gov/pubmed/28587231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md15060164
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