Induction of p53-Independent Apoptosis and G1 Cell Cycle Arrest by Fucoidan in HCT116 Human Colorectal Carcinoma Cells

It is well known that fucoidan, a natural sulfated polysaccharide present in various brown algae, mediates anticancer effects through the induction of cell cycle arrest and apoptosis. Nevertheless, the role of tumor suppressor p53 in the mechanism action of fucoidan remains unclear. Here, we investi...

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Pubblicato in:Mar Drugs
Autori principali: Park, Hye Young, Park, Shin-Hyung, Jeong, Jin-Woo, Yoon, Dahye, Han, Min Ho, Lee, Dae-Sung, Choi, Grace, Yim, Mi-Jin, Lee, Jeong Min, Kim, Do-Hyung, Kim, Gi-Young, Choi, Il-Whan, Kim, Suhkmann, Kim, Heui-Soo, Cha, Hee-Jae, Choi, Yung Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484104/
https://ncbi.nlm.nih.gov/pubmed/28555064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md15060154
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