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Total Synthesis of Brevenal
This manuscript describes the total synthesis of the marine ladder toxin brevenal utilizing a convergent synthetic strategy. Critical to the success of this work was the use of olefinic-ester cyclization reactions and the utilization of glycal epoxides as precursors to C–C and C–H bonds.
Enregistré dans:
| Publié dans: | J Am Chem Soc |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484051/ https://ncbi.nlm.nih.gov/pubmed/21322562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja200089f |
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