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A Practical Total Synthesis of Globo-H for Use in Anticancer Vaccines
[Image: see text] An improved synthesis of the hexasaccharide MBr1 antigen (globo-H) is reported. Enhanced efficiency in the synthesis was necessary for the scale up production of globo-H, in order to advance globo-H based anticancer vaccines to clinical trials. The key features of the improved synt...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3016894/ https://ncbi.nlm.nih.gov/pubmed/19874068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo901682p |
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