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Postinduction repression of the beta-interferon gene is mediated through two positive regulatory domains.

Virus induction of the human beta-interferon (beta-IFN) gene results in an increase in the rate of beta-IFN mRNA synthesis, followed by a rapid postinduction decrease. In this paper, we show that two beta-IFN promoter elements, positive regulatory domains I and II (PRDI and PRDII), which are require...

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Detalles Bibliográficos
Main Authors: Whittemore, L A, Maniatis, T
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC54837/
https://ncbi.nlm.nih.gov/pubmed/2172963
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