In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

Due to its relatively slow clinical progression, B cell chronic lymphocytic leukemia (B-CLL) is classically described as a disease of accumulation rather than proliferation. However, evidence for various forms of clonal evolution suggests that B-CLL clones may be more dynamic than previously assumed...

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Main Authors: Messmer, Bradley T., Messmer, Davorka, Allen, Steven L., Kolitz, Jonathan E., Kudalkar, Prasad, Cesar, Denise, Murphy, Elizabeth J., Koduru, Prasad, Ferrarini, Manlio, Zupo, Simona, Cutrona, Giovanna, Damle, Rajendra N., Wasil, Tarun, Rai, Kanti R., Hellerstein, Marc K., Chiorazzi, Nicholas
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC548318/
https://ncbi.nlm.nih.gov/pubmed/15711642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523409
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