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Prohibitin-induced obesity leads to anovulation and polycystic ovary in mice

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and the most common cause of female infertility. However, its etiology and underlying mechanisms remain unclear. Here we report that a transgenic obese mouse (Mito-Ob) developed by overexpressing prohibitin in adipocytes develops pol...

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Detaylı Bibliyografya
Yayımlandı:Biol Open
Asıl Yazarlar: Ande, Sudharsana Rao, Nguyen, Khanh Hoa, Xu, Yang Xin Zi, Mishra, Suresh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483017/
https://ncbi.nlm.nih.gov/pubmed/28432106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.023416
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