Loading...

Prohibitin-induced, obesity-associated insulin resistance and accompanying low-grade inflammation causes NASH and HCC

Obesity increases the risk for nonalcoholic steatohepatitis (NASH) and hepatocarcinogenesis. However, the underlying mechanisms involved in the disease process remain unclear. Recently, we have developed a transgenic obese mouse model (Mito-Ob) by prohibitin mediated mitochondrial remodeling in adip...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Ande, Sudharsana R., Nguyen, K. Hoa, Grégoire Nyomba, B. L., Mishra, Suresh
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804274/
https://ncbi.nlm.nih.gov/pubmed/27005704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23608
Tags: Add Tag
No Tags, Be the first to tag this record!