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Prohibitin-induced, obesity-associated insulin resistance and accompanying low-grade inflammation causes NASH and HCC

Obesity increases the risk for nonalcoholic steatohepatitis (NASH) and hepatocarcinogenesis. However, the underlying mechanisms involved in the disease process remain unclear. Recently, we have developed a transgenic obese mouse model (Mito-Ob) by prohibitin mediated mitochondrial remodeling in adip...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Ande, Sudharsana R., Nguyen, K. Hoa, Grégoire Nyomba, B. L., Mishra, Suresh
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804274/
https://ncbi.nlm.nih.gov/pubmed/27005704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23608
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